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2026-08-18
10 min read

Demystifying UART, SPI, and I2C: The High-Speed Communication Protocols of Hardware

Demystifying UART, SPI, and I2C: The High-Speed Communication Protocols of Hardware

Demystifying UART, SPI, and I2C: The High-Speed Communication Protocols of Hardware

When you connect a sensor, an OLED display, or a GPS module to an ESP32 or STM32 microcontroller, how do they talk to each other? They don't have ethernet ports or HTTP REST APIs.

Instead, microchips communicate using low-level serial protocols. The three most common hardware buses in embedded systems are UART, I2C, and SPI.

At Kone Lab, we teach students to diagnose these physical waveforms using oscilloscopes and logic analyzers. Here is how they compare.


1. UART: The Asynchronous Point-to-Point Wire

UART (Universal Asynchronous Receiver-Transmitter) is an asynchronous, point-to-point communication channel.

ARCHITECTURE SCHEMATIC
flowchart LR subgraph MCU["Host Microcontroller (Transceiver 1)"] TX1["UART TX (Transmit)"] RX1["UART RX (Receive)"] GND1["GND (Signal Ground)"] end subgraph Sensor["GPS / Peripheral (Transceiver 2)"] RX2["UART RX (Receive)"] TX2["UART TX (Transmit)"] GND2["GND (Signal Ground)"] end TX1 -->|Asynchronous Serial Data| RX2 TX2 -->|Asynchronous Serial Data| RX1 GND1 <-->|Common Voltage Reference| GND2 style MCU fill:#080d1a,stroke:#334155,stroke-width:1px,color:#f8fafc style Sensor fill:#080d1a,stroke:#334155,stroke-width:1px,color:#f8fafc style TX1 fill:#0f172a,stroke:#00d4ff,stroke-width:1px,color:#f8fafc style RX1 fill:#0f172a,stroke:#00d4ff,stroke-width:1px,color:#f8fafc style GND1 fill:#0f172a,stroke:#64748b,stroke-width:1px,color:#f8fafc style TX2 fill:#0f172a,stroke:#10b981,stroke-width:1px,color:#f8fafc style RX2 fill:#0f172a,stroke:#10b981,stroke-width:1px,color:#f8fafc style GND2 fill:#0f172a,stroke:#64748b,stroke-width:1px,color:#f8fafc

2. I2C: The Multi-Device Addressable Bus

I2C (Inter-Integrated Circuit) is a synchronous, two-wire multi-device bus developed by Philips (NXP).

* SDA (Serial Data): Carries the binary payload bits.

* SCL (Serial Clock): Pulsed by the master to synchronize data bit sampling.

// Reading an I2C Temperature Sensor (Arduino C++)
#include <Wire.h>

#define SENSOR_I2C_ADDR 0x48

void setup() {
  Wire.begin();
  Serial.begin(115200);
}

void loop() {
  Wire.beginTransmission(SENSOR_I2C_ADDR);
  Wire.write(0x00); // Request temperature register
  Wire.endTransmission();

  Wire.requestFrom(SENSOR_I2C_ADDR, 2);
  if (Wire.available() == 2) {
    int msb = Wire.read();
    int lsb = Wire.read();
    float tempC = ((msb << 8) | lsb) * 0.0625;
    Serial.printf("Current Temperature: %.2f C\n", tempC);
  }
  delay(1000);
}

3. SPI: The High-Speed Full-Duplex Bus

SPI (Serial Peripheral Interface) is designed for high bandwidth (typically 10 MHz to 80 MHz+).

* SCK (Serial Clock)

* MOSI (Master Out, Slave In)

* MISO (Master In, Slave Out)

* CS / SS (Chip Select / Slave Select)


Summary Comparison

MetricUARTI2CSPI
Wiring2 Wires2 Wires (SDA, SCL)4 Wires (MOSI, MISO, SCK, CS)
Typical SpeedUp to 115.2 kbps100 kbps – 3.4 MbpsUp to 80+ Mbps
Multi-Device?Point-to-Point onlyYes (127 devices by address)Yes (1 dedicated CS wire per chip)
Clock LineAsynchronous (No clock)SynchronousSynchronous

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